• ABOUT US

    Our vision is to pioneer therapy that would enhance the repair of damaged myelin sheaths that could revolutionize treatments for patients suffering from demyelinating disorders including multiple sclerosis.

  • Myelin Research

    Myelin is a fatty substance that wraps around axons. It protects and offers metabolic support to axons amongst its many functions. Demyelination leads to damage to this sheath, leading to a disruption in nerve impulse conduction.

  • Our Research

    Dr. Adebiyi spearheads groundbreaking research on adenosine receptor subtypes in multiple sclerosis and neuronal activity during demyelination

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Search for potential myelinogenetic compounds

Exploring novel compounds that can promote the recruitment, survival, differentiation, and
maturation of oligodendrocyte precursor cells.

Glia-glia interaction in demyelination

The intricate interplay of other glial cells (especially microglia and astrocytes) with oligodendrocytes during myelin degradation and repair.

Neurotoxicity and demyelination

Exposure to neurotoxic metals and environmental contaminants as a risk factor for the development of demyelinating disorders.

Molecular and Behavioural Neuroscience

Understanding the molecular mechanisms surrounding the failure of remyelination as well as behavioural alterations in several demyelinating disorders.

Myelin in Neurodegenerative and Neurotoxic Disorders (MyNND) lab

The MyNND lab investigates novel compounds/approaches that could promote remyelination in demyelinating diseases, understand how demyelination/remyelination contributes to changes in brain network connectivity and transgenerational exposure to emerging contaminants “forever chemicals” in animals as risk factors for demyelination/ neurodegenerative disorders.

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Journals and Publications

Embark on an intellectual journey as you peruse the distinguished publications authored by Dr. Adebiyi, a luminary in the field of neuroscience. Featured in leading journals, her groundbreaking research unravels the intricacies of adenosine receptor subtypes in the context of multiple sclerosis.

Delving deeper, she explores the dynamic interplay of neuronal activity during demyelination, offering fresh perspectives on the underlying mechanisms of neurological disorders.

Immerse yourself in the latest advancements at the intersection of science and discovery, where Dr. Adebiyi’s work not only expands our understanding of the nervous system but also paves the way for innovative approaches in neuroscientific research and therapeutic interventions.

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Roles of Adenosine Receptor (subtypes A1 and A2A) in Cuprizone-Induced  Hippocampal Demyelination Molecular Neurobiology

Adebiyi OE, Bynoe MS (2023)
Publisher's website

High environmental temperature: Insights into behavioural, Neurodevelopmental and Gut Microbiome changes following gestational exposure in rats

Adebiyi O, Adigun K, Adebiyi A, Odenibi B (2022)
Publisher's website

Neurocognitive domains and neuropathological changes in experimental infection with Trypanosoma brucei in Wistar rats

Adebiyi O, Omobowale T, Abatan M (2021)
Publisher's website

Beta-sitosterol enhances motor coordination, attenuates memory loss and demyelination in a vanadium-induced model of experimental neurotoxicity

Adebiyi OE, Olayemi FO, Olopade, JO, Tan NH. (2019)
Publisher's website

Join our Team

Join us! Openings at postdoctoral and graduate levels. Contact: o.adebiyi@usask.ca for details.
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